https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Divergent roles for clusterin in lung injury and repair https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31071 CLU−/−) mice persisted after bleomycin and it was associated with increased DNA damage, reduced DNA repair responses, and elevated cellular senescence. Remarkably, this pattern mirrored that observed in IPF lung tissues. Together, our results show that cellular localization of Clusterin leads to divergent effects on epithelial cell regeneration and lung repair during fibrosis.]]> Wed 24 Nov 2021 15:51:40 AEDT ]]> Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16917 Tue 31 Jul 2018 16:15:02 AEST ]]> Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45701 Tue 28 Mar 2023 15:44:53 AEDT ]]> Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30666 Thu 28 Oct 2021 13:04:12 AEDT ]]> miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29820 Sat 24 Mar 2018 07:40:51 AEDT ]]>